Collaborators

In my role as NMR facility manager I collaborate with most of the synthetic groups in the department providing NMR support to their endeavours. More details of these collaborations can be found on the recent results page of the NMR service site. I am always keen on developing interesting projects. Please get in touch if you feel my group can be of assistance.


Previous Collaborators

Dr. Adrian L. Davis (Pfizer Global Research and Development), Prof. John C. Mitchell and Prof. Martin J. Snowden (University of Greenwich) and Oxford Instruments developing applications of liquid-state DNP methodology (the HyperSense). This project was part of the Pfizer post-doctoral research fellow scheme at the University of Greenwich.

  1. I. J. Day, J. C. Mitchell, M. J. Snowden, and A. L. Davis.
    Investigation of the potential of the dissolution dynamic nuclear polarisation method for general sensitivity enhancement in small molecule NMR spectroscopy.
    Appl. Magn. Reson., 34:453-460, 2008. [ DOI ]
  2. I. J. Day, J. C. Mitchell, M. J. Snowden, and A. L. Davis.
    Co-acquisition of hyperpolarised 13C and 15N NMR spectra.
    Magn. Reson. Chem., 45(12):1018-1021, 2007. [ DOI ]
  3. I. J. Day, J. C. Mitchell, M. J. Snowden, and A. L. Davis.
    Applications of DNP-NMR for the measurement of heteronuclear T1 relaxation times.
    J. Magn. Reson., 187(2):216-224, 2007. [ DOI ]


Prof. P. J. Hore (University of Oxford) and Dr. Ken Hun Mok (Trinity College Dublin) developing stopped-flow NMR and photo-CIDNP methodologies for the study of protein folding and the structural investigation of partially structured proteins.

  1. K. H. Mok, L. T. Kuhn, M. Goez, I. J. Day, J. C. Lin, N. H. Andersen, and P. J. Hore.
    A pre-exisiting hydrophobic collapse in the unfolded state of an ultrafast folding protein.
    Nature, 447(7140):106-109, 2007. [ DOI ]
  2. K. H. Mok, T. Nagashima, I. J. Day, P. J. Hore, and C. M. Dobson.
    Multiple subsets of side-chain packing in partially folded states of α-lactalbumins.
    Proc. Natl. Acad. Sci. USA, 102(25):8899-8904, 2005. [ DOI ]
  3. K. H. Mok, T. Nagashima, I. J. Day, J. A. Jones, C. J. V. Jones, C. M. Dobson, and P. J. Hore.
    Rapid sample-mixing technique for transient NMR and Photo-CIDNP spectroscopy: Applications to real-time protein folding.
    J. Am. Chem. Soc., 125(41):12484-12492, 2003. [ DOI ]


Dr. Kevin H. Gardner (University of Texas, Southwestern Medical Center, Dallas) working on the development of time-resolved NMR spectroscopy to probe the conformational changes in a photo-active protein.

  1. S. M. Harper, L. C. Neil, I. J. Day, P. J. Hore, and K. H. Gardner.
    Conformational changes in a photosensory LOV domain monitored by time-resolved NMR spectroscopy.
    J. Am. Chem. Soc., 126(11):3390-3391, 2004. [ DOI ]